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SUMMARY:Promotionsvortrag Physik: Phenomenological Perspectives in Bio
 physics
UID:040000008200E00074C5B7101A82E00800000000F074C1CD406FDC010000000000
 00000010000000162F2A31C90BD443BF85C506E05FD0F2
DESCRIPTION:Ankündigung des Promotionsvortrags von: Herrn Conrad Möc
 kel In this thesis defense\, I present non-invasive\, label-free optic
 al approaches for quantifying biolog-ical material properties across s
 ubcellular length scales. A central focus lies on mass density\, which
  links molecular composition to mechanical behavior and transport phen
 omena\, yet is rarely measured directly. Simple mixture models relate 
 refractive index measurements to local mass density\, but the accuracy
 \, especially in complex biological matter\, is often limited by incom
 plete knowledge of the molecular composition. I show how this uncertai
 nty propagates and why it moti-vates direct density measurements. Stim
 ulated Brillouin scattering provides such a direct readout by exploiti
 ng photon-phonon interactions. I demonstrate its applicability to biol
 ogical matter and discuss how it can serve as a quantitative benchmark
  for refractive-index-based estimates\, broad-ening the scope of densi
 ty-based inferences in biological studies. In the second half of the t
 alk\, I discuss bright-field differential dynamic microscopy (DDM). By
  analyzing inherent density fluctua-tions in microscopy movies without
  the presence of exogenous labels or tracer particles\, DDM yields the
  intermediate scattering function across length and time scales. In Xe
 nopus laevis egg extract as a model system for cytoplasm\, I show how 
 DDM reveals viscoelastic subdiffusion and non-Gaussian displacement st
 atistics. Perturbations of biochemical activity and cytoskeletal or-ga
 nization modulate these dynamics and motivate the notion of hierarchic
 al heterogeneities in the cytoplasm. I close by outlining next steps a
 nd future directions. (Vortrag auf Englisch) Dem Vortrag schließt sic
 h eine Diskussion von 15 Minuten an. Vortrag und Diskussion sind öffe
 ntlich. Diesen Verfahrensteilen folgt ein nicht öffentliches Rigorosu
 m von 45 Minuten.
DTSTART:20260112T140000Z
DTEND:20260112T153000Z
LOCATION:SR 0.125\, Max-Planck-Zentrum für Physik und Medizin\, Kussm
 aulallee 2\, Erlangen
DTSTAMP:20260408T163434Z
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